Hepatitis B is one of the common infectious diseases which endanger public health seriously. About 10% of people in China are hepatitis B virus carriers (HBsAg positive), there are about 20 million chronic hepatitis patients, mainly through blood, sexual contact, close contact and other transmission, so the incidence of hepatitis B is familial. The occurrence of cirrhosis and liver cancer is closely related to it. Hepatitis B has caused a heavy economic burden to the patients, families and society, so that many families are poor because of illness, because of illness back to poverty, but also triggered a series of social problems, is one of the prominent public health problems in our country at the present stage. I briefly introduce how to do mother and child hepatitis B block, hope to be helpful to everyone.
What situations need to do mother-to-child block?
How to do mother-infant block?
What situations need to do mother-to-child block? Pregnant women with HBV DNA, HBsAg, HBeAg in any positive, the child after birth need to do mother-to-child block.
How to do mother-infant block? 1. After washing amniotic fluid, mother's blood and vaginal secretions after birth, venous blood should be drawn immediately to check HBV DNA, HBsAg and HBeAg.
2, within 2 hours of birth, the child was injected with 200IU of hepatitis B immunoglobulin on one side of the triceps, while one dose of hepatitis B vaccine was injected into the other side of the triceps.
3, if the test of HBV DNA, HBsAg, HBeAg has a positive, 2 weeks after the injection of 200IU hepatitis B immunoglobulin.
4, when the child was born at 1 month and 6 months, then intramuscular injection of 1 hepatitis B vaccine.
5, at 7 months of birth, HBsAb is positive, and immunity to hepatitis B is formed. If it is negative, hepatitis B vaccine needs to be strengthened again, and it still needs to be implemented according to 0, 1, and 6. If it is weak positive, it is recommended to strengthen the injection of 1 hepatitis B vaccine.
6. HBV DNA, HBsAg and HBeAg were re-examined at 4 weeks after birth. If HBeAg was still positive and HBV DNA was significantly decreased, 200IU hepatitis B immunoglobulin was injected again. Review at 3 months of birth, if HBV DNA and HBsAg turn negative, the mother-to-child block is successful. If there is no significant decline or continued rise, the possibility of mother-to-child interruption is very small. After 7 months of birth, if HBcAb decreased significantly,HBsAb increased significantly, and HBV DNA turned negative, the mother-to-child block was successful. If the HBV DNA at this time is more than 10 to the fourth power, the mother-to-child block fails. If HBV DNA is below 10 to the third power, wait until 18 months after birth to review, if HBsAg turns negative, the mother-to-child block is successful; Otherwise, failure is declared.